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Última actualización: 17 enero 2017


DICIEMBRE 2016
  • Palman J, May J, Pilkington C.
    Macrophage activation syndrome triggered by coeliac disease: a unique case report.
    Pediatr Rheumatol Online J. 2016 Dec 9;14(1):66.
    https://www.ncbi.nlm.nih.gov/pubmed/27938384
  • Bracaglia C, de Graaf K, Pires Marafon D, Guilhot F, Ferlin W, Prencipe G, Caiello I, Davì S, Schulert G, Ravelli A, Grom AA, de Min C, De Benedetti F.
    Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
    Ann Rheum Dis. 2017 Jan;76(1):166-172.
    https://www.ncbi.nlm.nih.gov/pubmed/27296321

NOVIEMBRE 2016
  • García-Montoya L, Sáenz-Tenorio CN, Janta I, Menárguez J, López-Longo FJ, Monteagudo I, Naredo E.
    Hemophagocytic lymphohistiocytosis in a patient with Sjögren's syndrome: case report and review.
    Rheumatol Int. 2016 Nov 16.
    https://www.ncbi.nlm.nih.gov/pubmed/27853859

OCTUBRE 2016
  • Aytaç S, Batu ED, Ünal Ş, Bilginer Y, Çetin M, Tuncer M, Gümrük F, Özen S.
    Macrophage activation syndrome in children with systemic juvenile idiopathic arthritis and systemic lupus erythematosus
    Rheumatol Int. 2016 Oct;36(10):1421-9
    https://www.ncbi.nlm.nih.gov/pubmed/27510530

SEPTIEMBRE 2016
  • Hernández-Jiménez P,Díaz-Pedroche C, Laureiro J, Madrid O, Martín E, Lumbreras C.
    Hemophagocytic lymphohistiocytosis: Analysis of 18 cases.
    Med Clin (Barc). 2016 Oct 7.
    https://www.ncbi.nlm.nih.gov/pubmed/27726848
  • Wunderlich M, Stockman C, Devarajan M, Ravishankar N, Sexton C, Kumar AR, Mizukawa B, Mulloy JC.
    A xenograft model of macrophage activation syndrome amenable to anti-CD33 and anti-IL-6R treatment.
    JCI Insight. 2016 Sep 22;1(15):e88181.
    https://www.ncbi.nlm.nih.gov/pubmed/27699249
  • Thomas W, Veer MV, Besser M.
    Haemophagocytic lymphohistiocytosis: an elusive syndrome.
    Clin Med (Lond). 2016 Oct;16(5):432-436.
    https://www.ncbi.nlm.nih.gov/pubmed/27697804
  • Ruscitti P, Cipriani P, Ciccia F, Masedu F, Liakouli V, Carubbi F, Berardicurti O, Guggino G, Di Benedetto P, Di Bartolomeo S, Valenti M, Triolo G,  Giacomelli R.
    Prognostic factors of macrophage activation syndrome, at the time of diagnosis, in adult patients affected by autoimmune disease: Analysis of 41 cases collected in 2 rheumatologic centers.
    Autoimmun Rev. 2016 Sep 21. [Epub ahead of print]
    https://www.ncbi.nlm.nih.gov/pubmed/27664384
  • Crayne CB, Khatami KS, Galliano G.
    Macrophage Activation Syndrome.
    Clin Pediatr (Phila). 2016 Oct;55(11):1001-4.
    https://www.ncbi.nlm.nih.gov/pubmed/27562237

AGOSTO 2016
  • Aytaç S, Batu ED, Ünal Ş, Bilginer Y, Çetin M, Tuncer M, Gümrük F, Özen S.
    Macrophage activation syndrome in children with systemic juvenile idiopathic arthritis and systemic lupus erythematosus.
    Rheumatol Int. 2016 Oct;36(10):1421-9.
    http://www.ncbi.nlm.nih.gov/pubmed/27510530
  • Bracaglia C, de Graaf K, Pires Marafon D, Guilhot F, Ferlin W, Prencipe G, Caiello I, Davì S, Schulert G, Ravelli A, Grom AA, de Min C, De Benedetti F.
    Elevated circulating levels of interferon-γ and interferon-γ-induced chemokines characterise patients with macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
    Ann Rheum Dis. 2016 Jun 13. pii: annrheumdis-2015-209020. doi: 10.1136/annrheumdis-2015-209020. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/27296321

JUNIO 2016
  • Gormezano NW, Otsuzi CI, Barros DL, da Silva MA, Pereira RM, Campos LM, Borba EF, Bonfá E, Silva CA.
    Macrophage activation syndrome: A severe and frequent manifestation of acute pancreatitis in 362 childhood-onset compared to 1830 adult-onset systemic lupus erythematosus patients.
    Semin Arthritis Rheum. 2016 Jun;45(6):706-10. doi: 10.1016/j.semarthrit.2015.10.015
    http://www.ncbi.nlm.nih.gov/pubmed/26833399
MARZO 2016
  • Grom AA, Horne A, De Benedetti F.
    Macrophage activation syndrome in the era of biologic therapy.
    Nat Rev Rheumatol. 2016 Mar 24. doi: 10.1038/nrrheum.2015.179. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/27009539

FEBRERO 2016
  • Put K, Brisse E, Avau A, Imbrechts M, Mitera T, Janssens R, Proost P, Fallarino F, Wouters CH, Matthys P.
    IDO1 Deficiency Does Not Affect Disease in Mouse Models of Systemic Juvenile Idiopathic Arthritis and Secondary Hemophagocytic Lymphohistiocytosis.
    PLoS One. 2016 Feb 25;11(2):e0150075. doi: 10.1371/journal.pone.0150075. eCollection 2016.
    http://www.ncbi.nlm.nih.gov/pubmed/26914138
  • Tasaki Y, Shimizu M, Inoue N, Mizuta M, Nakagishi Y, Wada T, Yachie A.
    Disruption of vascular endothelial homeostasis in systemic juvenile idiopathic arthritis-associated macrophage activation syndrome: The dynamic roles of angiopoietin-1 and -2.
    Cytokine. 2016 Feb 20;80:1-6. doi: 10.1016/j.cyto.2016.02.008. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/26908294

ENERO 2016
  • Grom AA, Ilowite NT, Pascual V, Brunner HI, Martini A, Lovell D, Ruperto N; Paediatric Rheumatology International Trials Organisation and the Pediatric Rheumatology Collaborative Study Group, Leon K, Lheritier K, Abrams K.
    Rate and Clinical Presentation of Macrophage Activation Syndrome in Patients With Systemic Juvenile Idiopathic Arthritis Treated With Canakinumab.
    Arthritis Rheumatol. 2016 Jan;68(1):218-28. doi: 10.1002/art.39407.
    http://onlinelibrary.wiley.com/doi/10.1002/art.39407/abstract

DICIEMBRE 2015
  • Boom V, Anton J, Lahdenne P, Quartier P, Ravelli A, Wulffraat NM, Vastert SJ
    Evidence-based diagnosis and treatment of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
    Pediatr Rheumatol Online J. 2015 Dec 3;13(1):55. doi: 10.1186/s12969-015-0055-3.
    http://www.ncbi.nlm.nih.gov/pubmed/26634252

OCTUBRE 2015
  • Ravelli A, Davì S, Minoia F, Martini A, Cron RQ.
    Macrophage Activation Syndrome
    Hematol Oncol Clin North Am. 2015 Oct;29(5):927-41.
    http://www.ncbi.nlm.nih.gov/pubmed/26461152
  • Ravelli A, Minoia F, Davì S, Horne A, Bovis F, Pistorio A, Aricò M, Avcin T, Behrens EM, De Benedetti F, Filipovich L, Grom AA, Henter JI, Ilowite NT, Jordan MB, Khubchandani R, Kitoh T, Lehmberg K, Lovell DJ, Miettunen P, Nichols KE, Ozen S, Pachlopnick-Schmid J, Ramanan AV, Russo R, Schneider R, Sterba G, Uziel Y, Wallace C, Wouters C, Wulffraat N, Demirkaya E, Brunner HI, Martini A, Ruperto N, Cron RQ; Pediatric Rheumatology International Trials Organization; Childhood Arthritis & Rheumatology Research Alliance; Pediatric Rheumatology Collaborative Study Group; Histiocyte Society.
    Development and initial validation of classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
    Arthritis Rheumatol. 2015 Aug 28. doi: 10.1002/art.39332. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/26314788
  • Grom AA, Ilowite NT, Pascual V, Brunner HI, Martini A, Lovell D, Ruperto N; Paediatric Rheumatology International Trials Organisation (PRINTO); Pediatric Rheumatology Collaborative Study Group (PRCSG), Leon K, Lheritier K, Abrams K.
    Canakinumab in Systemic Juvenile Idiopathic Arthritis: Impact on the Rate and Clinical Presentation of Macrophage Activation Syndrome.
    Arthritis Rheumatol. 2015 Aug 28. doi: 10.1002/art.39407. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/26314396 

AGOSTO 2015
  • Cifaldi L, Prencipe G, Caiello I, Bracaglia C, Locatelli F, De Benedetti F, Strippoli R.
    Inhibition of Natural Killer Cell Cytotoxicity by Interleukin-6: Implications for the Pathogenesis of Macrophage Activation Syndrome.
    Arthritis Rheumatol. 2015 Aug 5. doi: 10.1002/art.39295. EPUB ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/26251193

JULIO 2015
  • Shimizu M, Nakagishi Y, Inoue N, Mizuta M, Ko G, Saikawa Y, Kubota T, Yamasaki Y, Takei S, Yachie A
    Interleukin-18 for predicting the development of macrophage activation syndrome in systemic juvenile idiopathic arthritis.
    Clin Immunol. 2015 Jun 20;160(2):277-281. doi: 10.1016/j.clim.2015.06.005. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/26101092

JUNIO 2015
  • Minoia F, Davì S, Horne A, Bovis F, Demirkaya E, Akikusa J, Ayaz NA, Al-Mayouf SM, Barone P, Bica B, Bolt I, Breda L, De Cunto C, Enciso S, Gallizzi R, Griffin T, Hennon T, Horneff G, Jeng M, Kapovic AM, Lipton JM, Magni Manzoni S, Rumba-Rozenfelde I, Magalhaes CS, Sewairi WM, Stine KC, Vougiouka O, Weaver LK, Davidsone Z, De Inocencio J, Ioseliani M, Lattanzi B, Tezer H, Buoncompagni A, Picco P, Ruperto N, Martini A, Cron RQ, Ravelli A; Pediatric Rheumatology International Trials Organization; Childhood Arthritis and Rheumatology Research Alliance; Pediatric Rheumatology Collaborative Study Group; and the Histiocyte Society.
    Dissecting the Heterogeneity of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis.
    J Rheumatol June 2015 42(6):994-1001, doi:10.3899/jrheum.141261
    http://www.ncbi.nlm.nih.gov/pubmed/25877504

ABRIL 2015
  • Minoia F, Davì S, Horne A, Bovis F, Demirkaya E, Akikusa J, Ayaz NA, Al-Mayouf SM, Barone P, Bica B, Bolt I, Breda L, De Cunto C, Enciso S, Gallizzi R, Griffin T, Hennon T, Horneff G, Jeng M, Kapovic AM, Lipton JM, Magni Manzoni S, Rumba-Rozenfelde I, Magalhaes CS, Sewairi WM, Stine KC, Vougiouka O, Weaver LK, Davidsone Z, De Inocencio J, Ioseliani M, Lattanzi B, Tezer H, Buoncompagni A, Picco P, Ruperto N, Martini A, Cron RQ, Ravelli A; Pediatric Rheumatology International Trials Organization; Childhood Arthritis and Rheumatology Research Alliance; Pediatric Rheumatology Collaborative Study Group; and the Histiocyte Society.
    issecting the Heterogeneity of Macrophage Activation Syndrome Complicating Systemic Juvenile Idiopathic Arthritis.
    J Rheumatol. 2015 Apr 15. pii: jrheum.141261. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/25877504  
  • Rigante D, Emmi G, Fastiggi M, Silvestri E, Cantarini L.
    Macrophage activation syndrome in the course of monogenic autoinflammatory disorders.

    Clin Rheumatol. 2015 Apr 8. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/25846831

MARZO 2015
  • Put K, Avau A, Brisse E, Mitera T, Put S, Proost P, Bader-Meunier B, Westhovens R, Van den Eynde BJ, Orabona C, Fallarino F, De Somer L, Tousseyn T, Quartier P, Wouters C, Matthys P.
    Cytokines in systemic juvenile idiopathic arthritis and haemophagocytic lymphohistiocytosis: tipping the balance between interleukin-18 and interferon-γ.
    Rheumatology (Oxford). 2015 Mar 12. pii: keu524. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/25767156

FEBRERO 2015
  • Yokota S, Itoh Y, Morio T, Sumitomo N, Daimaru K, Minota S.
    Macrophage Activation Syndrome in Patients with Systemic Juvenile Idiopathic Arthritis under Treatment with Tocilizumab.
    J Rheumatol. 2015 Feb 15.
    http://www.ncbi.nlm.nih.gov/pubmed/25684767

SEPTIEMBRE 2014
  • Fardet L, Galicier L, Lambotte O, Marzac C, Aumont C, Chahwan D, Coppo P, Hejblum G.
    Development and validation of a score for the diagnosis of reactive hemophagocytic syndrome (HScore).
    Arthritis Rheumatol. 2014 Sep; 66(9):2613-2620.
    http://www.ncbi.nlm.nih.gov/pubmed/24782338

JULIO 2014
  • Davì S, Minoia F, Pistorio A, Horne A, Consolaro A, Rosina S, Bovis F et al on behalf of the Pediatric Rheumatology International Trials Organization; the Childhood Arthritis & Rheumatology Research Alliance; the Pediatric Rheumatology Collaborative Study Group; the Histiocyte Society.
    Performance of current guidelines for diagnosis of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis.
    Arthritis Rheumatol. 2014 Jul 7. doi: 10.1002/art.38769. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/25044674
  • Kaufman KM, Linghu B, Szustakowski JD, Husami A, Yang F, Zhang K, Filipovich A, Fall N, Harley JB, Nirmala NR, Grom AA.
    Whole exome sequencing reveals overlap between macrophage activation syndrome in systemic juvenile idiopathic arthritis and familial hemophagocytic lymphohistiocytosis.
    Arthritis Rheumatol. 2014 Jul 21. doi: 10.1002/art.38793. [Epub ahead of print].
    http://www.ncbi.nlm.nih.gov/pubmed/25047945
  • Minoia F, Davì S, Horne A, Demirkaya E, Bovis F, Li C et al on behalf of the Pediatric Rheumatology International Trials Organization; the Childhood Arthritis& Rheumatology Research Alliance; the Pediatric Rheumatology Collaborative Study Group, and the Histiocyte Society.
    Clinical features, treatment and outcome of macrophage activation syndrome complicating systemic juvenile idiopathic arthritis. A multinational, multicenter study of 362 patients.
    Arthritis Rheumatol. 2014 Jul 30. doi: 10.1002/art.38802.
    http://www.ncbi.nlm.nih.gov/pubmed/25077692

MAYO 2014
  • Poddighe D, Cavagna L, Brazzelli V, Bruni P, Marseglia GL.
    A hyper-ferritinemia syndrome evolving in recurrent macrophage activation syndrome, as an onset of amyopathic juvenile dermatomyositis: A challenging clinical case in light of the current diagnostic criteria.
    Autoimmun Rev. 2014 May 29. pii: S1568-9972(14)00128-1. doi: 10.1016/j.autrev.2014.05.009. [Epub ahead of print].
    http://www.ncbi.nlm.nih.gov/pubmed/24879966

ENERO 2014
  • Reddy VV, Myles A, Cheekatla SS, Singh S, Aggarwal A.
    Soluble CD25 in serum: a potential marker for subclinical macrophage activation syndrome in patients with active systemic onset juvenile idiopathic arthritis.
    Int J Rheum Dis. 2014 Jan 13. doi: 10.1111/1756-185X.12196. [Epub ahead of print]
    http://www.ncbi.nlm.nih.gov/pubmed/24417800

JUNIO 2013
  • Lehmberg K, Pink I, Eulenburg C, Beutel K, Maul-Pavicic A, Janka G.
    Differentiating macrophage activation syndrome in systemic juvenile idiopathic arthritis from other forms of hemophagocytic lymphohistiocytosis.
    J Pediatr. 2013 Jun;162(6):1245-51. doi: 10.1016/j.jpeds.2012.11.081. Epub 2013 Jan 17.
    http://www.ncbi.nlm.nih.gov/pubmed/23333131

MAYO 2013
  • Kahn PJ,Cron RQ
    Higher-dose Anakinra Is Effective in a Case of Medically Refractory Macrophage Activation Syndrome.
    J Rheumatol 2013 May;40(5):743-4. doi: 10.3899/jrheum.121098.
    http://www.ncbi.nlm.nih.gov/pubmed/23637382
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